PERSONALISING ANTICANCER DRUG COMBINATIONS

Cancer Research has led to the development of a new type of anticancer agents called "targeted molecules" which aim to specifically target a particular protein. They are generaly administered in combination with cytotoxic drugs which create DNA damage potentially leading to cell death. Our Research focuses on developping mathematical models ale to predict optimal drug combinations fro each individual patient. Those models are informed by multiple datasets measured in individual patients including tumor multi-omics information.


IN SILICO CLINICAL TRIAL

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Mathematical models may allow to guide patient selection in classical clinical trials testing a fixed drug combinations. They also offer the opportunity of a new type of clinicial trials in which  patients would receive personalised drug combinations predicted as optimal by the models.

CONTACT US

Unité INSERM U935

Campus du CNRS

Bâtiment A, 3ème étage
7 rue Guy Moquet
94801 Villejuif cedex
France
  • +33 (0)1 49 58 34 81

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